15th-century physician Robert Briand runs a leper colony that accepts new residents who suffer from the ravages of syphilis. When the beautiful Marie-Blanche is brought to the grim, prison-like facility, Briand finds she displays no apparent signs of disease. He risks everything when he falls in love with the woman and makes plans to run away with her.

Robert Briand
Marte-Blanche
Thérèse
Laurent Vita
Philippe
Cigal
Pedlar
Sodomite
Olivia
François, guard
Robert's Father
Eleonore